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Saint Isidore of Seville (; Latin: Isidorus Hispalensis; c. 560 - 4 April 636), a scholar and, for over three decades, Archbishop of Seville, is widely regarded as the last of the Fathers of the Church, as the 19th-century historian Montalembert put it in an oft-quoted phrase, "The last scholar of the ancient world." At a time of disintegration of classical culture, and aristocratic violence and illiteracy, he was involved in the conversion of the Arian Visigothic kings to Catholicism, both assisting his brother Leander of Seville, and continuing after his brother's death. He was influential in the inner circle of Sisebut, Visigothic king of Hispania. Like Leander, he played a prominent role in the Councils of Toledo and Seville.

Isidore was the first Christian writer to try to compile a summa of universal knowledge, in his most important work, the Etymologiae (taking its title from the method he uncritically used in the transcription of his era's knowledge). It is also known by classicists as the Origines (the standard abbreviation being Orig). This encyclopedia -- the first such Christian epitome--formed a huge compilation of 448 chapters in 20 volumes.  In it, as Isidore entered his own terse digest of Roman handbooks, miscellanies and compendia, he continued the trend towards abridgements and summaries that had characterised Roman learning in Late Antiquity. In the process, many fragments of classical learning are preserved which otherwise would have been hopelessly lost; "in fact, in the majority of his works, including the Origines, he contributes little more than the mortar which connects excerpts from other authors, as if he was aware of his deficiencies and had more confidence in the stilus maiorum than his own" his translator Katherine Nell MacFarlane remarks;  Some of these fragments were lost in the first place because Isidore's work was so highly regarded--Braulio called it quecunque fere sciri debentur, "practically everything that it is necessary to know"-- that it superseded the use of many individual works of the classics themselves, which were not recopied and have therefore been lost: "all secular knowledge that was of use to the Christian scholar had been winnowed out and contained in one handy volume; the scholar need search no further".  The fame of this work imparted a new impetus to encyclopedic writing, which bore abundant fruit in the subsequent centuries of the Middle Ages. It was the most popular compendium in medieval libraries. It was printed in at least ten editions between 1470 and 1530, showing Isidore's continued popularity in the Renaissance. Until the 12th century brought translations from Arabic sources, Isidore transmitted what western Europeans remembered of the works of Aristotle and other Greeks, although he understood only a limited amount of Greek. The Etymologiae was much copied, particularly into medieval bestiaries.

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Isidore of Seville