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The Mothers of Invention were an American rock band from California that served as the backing musicians for Frank Zappa. Formed in 1964, their work is marked by the use of sonic experimentation, innovative album art, and elaborate live shows. Originally an R&B band called the Soul Giants, the band's first lineup included Ray Collins, David Coronado, Ray Hunt, Roy Estrada and Jimmy Carl Black. Zappa was asked to take over as the guitarist following a fight between Collins and Coronado, the band's original saxophonist/leader.

The Soul Giants were formed in 1964. In 1964, Frank Zappa was approached by Ray Collins who asked him to take over as the guitarist following a fight between Collins and the group's original guitarist. Zappa accepted, and convinced the other members that they should play his music to increase the chances of getting a record contract. Original leader David Coronado did not think that the band would be employable if they played original material, and left the band. Zappa soon assumed leadership and the role as co-lead singer, even though he never considered himself a singer.  The band was renamed the Mothers, coincidentally on Mother's Day. The group increased their bookings after beginning an association with manager Herb Cohen, while they gradually gained attention on the burgeoning Los Angeles underground music scene. In early 1966, they were spotted by leading record producer Tom Wilson when playing Zappa's "Trouble Every Day," a song about the Watts Riots. Wilson had earned acclaim as the producer for singer-songwriter Bob Dylan and the folk-rock act Simon & Garfunkel, and was notable as one of the few African Americans working as a major label pop music producer at this time.  Wilson signed the Mothers to the Verve Records division of MGM Records, which had built up a strong reputation in the music industry for its releases of modern jazz recordings in the 1940s and 1950s, but was attempting to diversify into pop and rock audiences. Verve insisted that the band officially rename themselves because "Mother" in slang terminology was short for "motherfucker"--a term that apart from its profanity, in a jazz context connotes a very skilled musical instrumentalist. The label suggested the name "The Mothers Auxiliary", which prompted Zappa to come up with the name "The Mothers of Invention".
The Mothers of Invention