Jackson was born in Los Angeles, California, and grew up in the Crenshaw neighborhood of Los Angeles. He attended Long Beach Polytechnic High School, the same high school as future Philadelphia Eagles teammate Winston Justice and many other current NFL players. He became one of the top wide receiver recruits in the nation, with many collegiate football programs pursuing his services. He was named the 2004 Glenn Davis Award winner by the Los Angeles Times as Southern California's player of the year.

Jackson attended the University of California, where he played for the California Golden Bears football team from 2005 to 2007. Wearing the number 1, in his first collegiate game against Sacramento State in 2005, he scored both an offensive and special teams touchdown, returning a punt 49 yards for a score. Throughout his freshman season, Jackson picked up 38 receptions for 601 yards along with seven touchdowns, eclipsing the 100-yard mark three times. In the 2005 Las Vegas Bowl game against BYU, Jackson tallied 130 yards and two scores. Jackson was also expected to play for Cal's baseball team but, due to the success of his freshman football season, he chose to focus exclusively on football.  Coming into his sophomore year with high expectations, Jackson displayed more of his talent and playmaking ability, tallying 1,060 receiving yards and nine touchdowns. Jackson also returned four punts for touchdowns. He earned first-team All-Pac-10 honors as both a punt returner and a wide receiver. Jackson garnered national recognition with selections to first-team All-America by the Associated Press, Walter Camp Football Foundation, the Football Writers Association of America, the Sporting News, and Rivals.com as a punt returner. Jackson also captured the inaugural Randy Moss Award as the top returner in the nation. In one of only two California losses in Pac-10 play, Jackson had a 95-yard punt return for a touchdown against Arizona.  Jackson entered his junior season being considered a Heisman Trophy candidate. His season began promisingly, with a 77-yard punt return for a touchdown against Tennessee in the opening game of the season. Against eleventh-ranked Oregon, he caught 11 passes for 161 yards and two touchdowns to lead the Bears to their first victory in Autzen Stadium since 1987. Jackson finished the 2007 season with 65 catches for 762 yards, and scored six touchdowns as a receiver. Jackson was named an All-American as a return specialist. Jackson suffered several minor injuries that limited his effectiveness at times during the season, along with a right thigh injury that forced him to miss most of the game against Washington and the Big Game against Stanford. He also missed the first quarter of the 2007 Armed Forces Bowl for violating undisclosed team rules.  Jackson left Cal following the 2007 season and declared for the 2008 NFL Draft. He departed holding Pac-10 records for punts returned for a touchdown both in a season (four) and in a career (six). Jackson ranks third all-time at California for receiving yards with 2,423 and receiving touchdowns with 22. He is sixth in receptions (162). Jackson finished with 52 career plays of 20 yards or more, making up 23 percent of his 226 touches.

Ask a question about this article.
Did he have other stats for his college career?