Answer by taking a quote from the following article:

Melissa Ellen Gilbert (born May 8, 1964) is an American actress and television director. Gilbert began her career as a child actress in the late 1960s appearing in numerous commercials and guest starring roles on television. From 1974 to 1984, she starred as Laura Ingalls Wilder, the daughter of Charles Ingalls (played by Michael Landon) on the NBC series Little House on the Prairie. During the run of Little House, Gilbert appeared in several popular television films, including The Diary of Anne Frank and The Miracle Worker.

After her break up with Rob Lowe, Gilbert left for New York City to star in the play A Shayna Maidel. Gilbert was set up with actor Bo Brinkman, a cousin of actors Randy Quaid and Dennis Quaid. The couple married on February 22, 1988, only seven weeks after her relationship with Rob Lowe ended. Gilbert became pregnant months later. On May 1, 1989, she gave birth to son Dakota Paul Brinkman. They divorced in 1992.  Only weeks after Gilbert's divorce filing, Bruce Boxleitner's former wife, Kathryn Holcomb, set Boxleitner up with Gilbert. Holcomb by then was married to actor Ian Ogilvy. Gilbert had met Boxleitner as a teenager when they both were on Battle of the Network Stars when Gilbert introduced herself, and she had a pin-up of him in her locker. But Boxleitner ignored her because she was a teen and he was many years older than she was. After reconnecting, the couple started dating on and off for over a year. They were engaged twice and Boxleitner broke up with her each time. After reuniting for a third time, they finally married on January 1, 1995, in her mother's living room. Gilbert quickly became pregnant, but went into premature labor more than two months before her due date. She gave birth to a son, Michael Garrett Boxleitner, named in honor of Michael Landon, on October 6, 1995. His middle name is in honor of Garrett Peckinpah, her friend Sandy Peckinpah's son, who had died suddenly of meningitis at age 16. Gilbert is also stepmother to Boxleitner's two sons with Holcomb, Sam (born 1980) and Lee (born 1985). On March 1, 2011, Gilbert announced that she and Boxleitner had separated. On August 22, 2011, Gilbert filed for divorce from Boxleitner.  On January 29, 2013, Gilbert's representative confirmed the actress's engagement to fellow actor Timothy Busfield. The couple married on April 24, 2013. Since July 2013, Gilbert and Busfield have resided in Howell, Michigan.

Did she ever remarry?
they finally married on January 1, 1995,