Dafydd Rhys "Dave" Williams OC (born May 16, 1954) is a Canadian physician, public speaker and a retired CSA astronaut. Williams was a mission specialist on two space shuttle missions. His first spaceflight, STS-90 in 1998, was a 16-day mission aboard Space Shuttle Columbia dedicated to neuroscience research. His second flight, STS-118 in August 2007, was flown by Space Shuttle Endeavour to the International Space Station.

He is a member of the College of Physicians and Surgeons of Ontario, the Ontario Medical Association, the College of Family Physicians of Canada, the Royal College of Physicians and Surgeons of Canada, the Canadian Association of Emergency Physicians, the Aerospace Medical Association, the Canadian Society for Aerospace Medicine, and the Canadian Aeronautics and Space Institute. Past affiliations include the Society for Neuroscience, the New York Academy of Science, and the Montreal Physiological Society.  Williams was awarded the Commonwealth Certificate of Thanks in 1973 and the Commonwealth Recognition Award (1975) for his contribution to the Royal Life Saving Society of Canada. Academic awards include the A.S. Hill Bursary, McGill University, in 1980; the Walter Hoare Bursary, McGill University, in 1981; and the J.W. McConnell Award, McGill University, from 1981 to 1983. He was named Faculty Scholar in 1982 and University Scholar in 1983 by the faculty of medicine at McGill University. In 1983, he also received the psychiatry prize and the Wood Gold Medal from the Faculty of Medicine and was named on the dean's honor list by the physiology department, at McGill University, for his postgraduate research. He was twice awarded the second prize for his participation in the University of Toronto Emergency Medicine Research Papers Program, in 1986, and 1988, and received top honors in that competition in 1987.  in 2011, Williams was inducted into the Canada's Aviation Hall of Fame. The following year, Williams was made an Officer of the Order of Canada in 2013 for his work in space exploration.

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Williams was made an Officer of the Order of Canada in 2013 for his work in space exploration.