Alice Paul was born on January 11, 1885, at Paulsdale in Mount Laurel Township, New Jersey. She was the eldest of four children of William Mickle Paul I (1850-1902) and Tacie Paul (nee Parry), and a descendant of William Penn, the Quaker founder of Pennsylvania. Her siblings were Willam, Helen, and Parry. She grew up in the Quaker tradition of public service; her ancestors included participants in the New Jersey Committee of Correspondence in the Revolutionary era and a state legislative leader in the 19th century.

While associated with the Women's Social and Political Union, Paul was arrested seven times and imprisoned three times. It was during her time in prison that Paul learned the tactics of civil disobedience from Emmeline Pankhurst. Chief among these tactics was demanding to be treated as a political prisoner upon arrest. This not only sent a message about the legitimacy of the suffragists to the public, but also had the potential to provide tangible benefits. In many European countries, including England, political prisoners were given a special status: "[T]hey were not searched upon arrest, not housed with the rest of the prisoner population, not required to wear prison garb, and not force-fed if they engaged in hunger strikes." Though arrested suffragettes often were not afforded the status of political prisoners, this form of civil disobedience provided a lot of press for the WSPU. For example, during a London arrest (after being denied political prisoner status), Paul refused to put on prisoner's clothing. After the prison matrons were unable to forcibly undress her, they requested assistance from male guards. This shockingly improper act provided extensive press coverage for the suffrage movement.  Another popular civil disobedience tactic used by the Suffragettes was hunger striking. The first WSPU related hunger strike was conducted by sculptor Marion Wallace Dunlop in June 1909. By that fall it was being widely used by WSPU members because of its effectiveness in publicizing their mistreatment and gaining quick release from prison wardens. Refusing food worked in securing an early release for Paul during her first two arrests. However, during her third prison stint, the warden ordered twice daily force-feeding to keep Paul strong enough to finish out her month-long sentence.  Though the prisons staunchly maintained that the force-feeding of prisoners was for their own benefit, Paul and other women described the process as torturous. At the end of her month in prison, Paul had developed severe gastritis. She was carried out of prison and immediately tended to by a doctor. However, after this event, her health was permanently scarred; she often developed colds and flu which would sometimes require hospitalization.

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While associated with the Women's Social and Political Union, Paul was arrested seven times and imprisoned three times.