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Rahul Bose was born to Rupen and Kumud Bose on 27 July 1967. He describes himself as "...half Bengali; one-fourth Punjabi and one-fourth Maharashtrian." Bose's first acting role was at age six when he played the lead in a school play, Tom, the Piper's Son.

Bose assisted in the relief efforts in the Andaman and Nicobar Islands after the 2004 Boxing Day tsunami. As a result of this work, Bose launched the Andaman and Nicobar Scholarship Initiative through his NGO, The Foundation. The scholarship program provides for the education of underprivileged children from the Andaman and Nicobar Islands.  Bose is associated with several charitable organizations such as Teach for India, Akshara Centre, Breakthrough, Citizens for Justice and Peace and the Spastics Society of India. He is closely associated with the Teach For India movement to eradicate inequity in education. In addition, he became the first Indian Oxfam global ambassador in 2007. He is the founder and chairman of The Group of Groups, an umbrella organisation for 51 Mumbai charitable organisations and NGOs. He is also an ambassador for the American India Foundation, the World Youth Peace Movement and Planet Alert. He was also a vocal proponent of Narmada Bachao Andolan and its efforts to halt the construction of the Narmada dam. He also recorded the Terre des hommes audio book Goodgoodi karna, gale lagana; Sparsh ke niyam sikhiye (English: Tickle and hugs: Learning the touching rules), which is designed to give children resources against sexual abuse.  Bose has given lectures on gender equality and human rights at Oxford and during the 2004 World Youth Peace Summit. In 2009, he toured Canada lecturing on global climate change under the auspices of Climate Action Network and demonstrated with protesters at the Copenhagen Climate Change Summit. In 2011, he worked in conjunction with Bhaichung Bhutia to raise funds for victims of the Sikkim earthquake.  At the 8th convocation of BRAC University Bangladesh on 17 February 2013, Bose delivered the convocation speech.
Rahul Bose