Straczynski was born in Paterson, New Jersey, and is the son of Charles Straczynski, a manual laborer, and Evelyn Straczynski (nee Pate). He was raised in Newark, New Jersey; Kankakee, Illinois; Dallas, Texas; Chula Vista, California, where he graduated from high school; and San Diego, California. Straczynski's family religion was Catholic, and he has Polish ancestry. His grandparents lived in the area which today belongs to Belarus, and fled to America from the Russian Revolution; his father was born in the U.S., and has lived in Poland, Germany and Russia.

Straczynski was a fan of the cartoon He-Man and the Masters of the Universe. He wrote a spec script in 1984 and sent it directly to Filmation. They purchased his script, bought several others, and hired him on staff. During this time he became friends with Larry DiTillio, and when Filmation produced the He-Man spinoff She-Ra: Princess of Power, they both worked as story editors on the show. However, Filmation refused to give them credit on-screen and Straczynski and DiTillio both left and found work with DIC on Jayce and the Wheeled Warriors.  Straczynski and DiTillio also worked to create an animated version of Elfquest but that project soon fell through when CBS attempted to retool the show to appeal to younger audiences.  While working on Jayce, Straczynski was hired to come aboard the Len Janson and Chuck Menville project to adapt the movie Ghostbusters to an animated version called The Real Ghostbusters. When Janson and Menville learned that there was not only a 13-episode order but a 65-episode syndication order as well, they decided that the workload was too much and that they would only work on their own scripts. DIC head Jean Chalopin asked Straczynski to take on the task of story editing the entire 78-episode block as well as writing his own scripts. After the show's successful first season, consultants were brought in to make suggestions for the show, including changing Janine to a more maternal character, giving every character a particular "job" (Peter is the funny one, Egon is the smart one, and Winston, the only black character, was to be the driver), and to add kids into the show. Straczynski left at this point and Janson and Menville took on the story editing job for the second network season. Straczynski then developed a show called Spiral Zone but left after only one script when his concept for the show was drastically altered and took his name off the series, substituting the pseudonym "Fettes Grey" (derived from the names of the grave robbers in The Body Snatcher).  Straczynski also wrote for CBS Storybreak, writing an adaptation of Evelyn Sibley Lampman's The Shy Stegosaurus of Cricket Creek.

what was that show about?