Jackson was born in Los Angeles, California, and grew up in the Crenshaw neighborhood of Los Angeles. He attended Long Beach Polytechnic High School, the same high school as future Philadelphia Eagles teammate Winston Justice and many other current NFL players. He became one of the top wide receiver recruits in the nation, with many collegiate football programs pursuing his services. He was named the 2004 Glenn Davis Award winner by the Los Angeles Times as Southern California's player of the year.

After skipping voluntary camp in the spring, Jackson reported to training camp earlier than most veterans. However, he was not speaking to the media and was said to be frustrated about how the Eagles are unwilling to negotiate a contract extension with him. Jackson was carted off the field after he suffered a back injury during the second full team workout of training camp on July 31, but the injury was not serious.  In a 35-32 victory over the Detroit Lions, Jackson had 135 receiving yards and a 45-yard catch-and-run touchdown pass. The following week against the Jacksonville Jaguars, Jackson caught a 61-yard touchdown and finished the game with five receptions for 153 yards. However, on October 3 and 10, Jackson caught only five passes for 43 total yards. He scored a pair of touchdowns on October 17 against the Atlanta Falcons, one on a 31-yard run and the second on a 34-yard reception from Kevin Kolb. During the game, he sustained a severe concussion after a collision with Atlanta cornerback Dunta Robinson, with both players assisted from the field. Jackson returned to play on November 7 against the Indianapolis Colts.  On November 15, after an altercation with Laron Landry, Jackson caught a then career best 88-yard touchdown pass from Michael Vick on the first play from scrimmage while Landry was covering him in 59-28 a Monday Night Football victory against the Washington Redskins. He surpassed this on December 12 when he had a 91-yard touchdown against the Dallas Cowboys and also finished the game with a personal best 210 receiving yards. Jackson again ended the regular season as the team's leading receiver with 1,056 yards. Answer this question using a quote from the following article:

What was the most significant thing in the 2010 season?
Jackson again ended the regular season as the team's leading receiver with 1,056 yards.