Answer by taking a quote from the following article:

Rise Against is an American melodic hardcore band from Chicago, Illinois, formed in 1999. The band's current line-up comprises vocalist/rhythm guitarist Tim McIlrath, lead guitarist Zach Blair, bassist Joe Principe and drummer Brandon Barnes. Former members are guitarists Dan Wlekinski, Kevin White, Todd Mohney and Chris Chasse, and drummer Toni Tintari. The band spent its first four years signed to the independent record label Fat Wreck Chords, on which they released two studio albums, The Unraveling (2001) and Revolutions per Minute (2003).

Rise Against was formed in 1999, by bassist Joe Principe and guitarist Dan Wleklinski. Before Rise Against, Principe and Wleklinski were members of the Chicago punk rock band 88 Fingers Louie. This band toured and recorded to moderate success, but disbanded on two separate occasions in the late 1990s. Following the second breakup, Principe and Wleklinski decided to form a new band called Transistor Revolt, and recruited drummer Toni Tintari, guitarist Kevin White, and lead vocalist Tim McIlrath. Principe met McIlrath in Indianapolis while attending a Sick of It All concert, and recalled seeing him perform with his previous band Baxter. Impressed with McIlrath's gritty vocals, Principe gave him a seven track demo he had recorded, and invited him to join the nascent band. McIlrath accepted the invitation, and dropped out of Northeastern Illinois University.  The initial jam sessions were problematic, as McIlrath was unaccustomed to Principe and Wleklinski's fast-paced style of play. McIlrath described these early sessions as "the meeting of different worlds and worlds colliding", and noted how many of his friends questioned the future of the band. Despite these early issues, they were able to self-publish the extended play (EP) Transistor Revolt in 2000. The EP attracted the attention of the local punk community, including Fat Mike, the lead vocalist of NOFX and co-founder of the independent record label Fat Wreck Chords. Fat Mike offered to sign the band to a recording contract, with the stipulation that they change their name. He gave some suggestions, like Jimmy Cracked Corn And The I Don't Cares, although none of the band members liked them. Tintari suggested Rise Against, to which the band agreed upon.  After signing with Fat Wreck Chords, Tintari and White left the band. The remaining members then spent the next few months looking for another drummer capable of playing double-time beats at a rapid pace. During this period, the band Good Riddance found their new drummer, and sent Rise Against the audition tape of their number two choice, Brandon Barnes. A mutual friend gave Barnes' phone number to Principe, and after listening to Transistor Revolt, Barnes accepted the band's invitation.

Did they have any issues that would later cause them problems?
but disbanded on two separate occasions in the late 1990s.