Answer by taking a quote from the following article:

Najm was born and raised in Tallahassee, Florida. His stage name is short for "Tallahassee Pain", and was chosen because of the hardships he experienced while living there. Najm was brought up in a Muslim household, but he has expressed his lack of interest in the concept of religion. At just three years old he got his first taste of the music business when a friend of the family, gospel jazz artist/producer Ben Tankard, allowed him to spend time and "twist the knobs" at his recording studio.

In mid-2006, T-Pain began work on his second album, now with the Zomba Label Group as well as Konvict Muzik and Jive Records. The album, titled Epiphany, was released on June 5, 2007. The album sold 171,000 records in its first week, reaching number one on the Billboard 200. The record has since sold 819,000 records in the United States.  The album was preceded by the lead single "Buy U a Drank (Shawty Snappin')" featuring Yung Joc in February 2007. The single reached number one on both the Hot 100 and Hot R&B/Hip-Hop Songs chart, becoming his first single to top charts. The album's second single, "Bartender", featuring Akon was released in June 2007 and reached number five on the Hot 100 and number nine on the Hot R&B/Hip-Hop Songs chart. The third and final single from the album, "Church", was released in October 2007 but failed to chart in the United States.  Speaking in May 2007 to noted UK R&B writer Pete Lewis, of the award-winning Blues & Soul about his reason for naming his second album 'Epiphany', T-Pain stated: "One of the two dictionary meanings of epiphany is 'a sudden moment of insight or revelation'. And to me the title 'Epiphany' signifies the moment I realized that, to make the best music I can, I needed to just go in the studio and be myself, and not concentrate so hard on following other people's formulas."  While promoting his second album, T-Pain made guest appearances on multiple songs by other artists. T-Pain was featured on "I'm a Flirt" (remix) by R. Kelly with T.I., "Outta My System" by Bow Wow, "Baby Don't Go" by Fabolous, "I'm So Hood" by DJ Khaled with many other rappers, "Shawty" by Plies, "Kiss Kiss" by Chris Brown, "Low" by Flo Rida, and "Good Life" by Kanye West. In two weeks in late 2007, T-Pain was featured on four top ten singles on the Billboard Hot 100 chart  "Good Life" with Kanye West later won the BET Award for Best Collaboration and was nominated in several other categories. In 2008, the single won a Grammy Award for Best Rap Song.

Did he work with any other artists?
"I'm a Flirt" (remix) by R. Kelly with T.I.,