Hamid Karzai , (Pashto/Dari: Hmd khrzy, born 24 December 1957) is an Afghan politician who was the leader of Afghanistan from 22 December 2001 to 29 September 2014, originally as an interim leader and then as President for almost ten years, from 7 December 2004 to 2014. He comes from a politically active family; Karzai's father, uncle and grandfather were all active in Afghan politics and government. Karzai and his father before him, Abdul Ahad Karzai, were each head of the Popalzai tribe of the Durrani tribal confederation.

In 1999, Hamid Karzai married Zeenat Quraishi, a gynaecologist by profession who was working as a doctor with Afghan refugees living in Pakistan. They have a son, Mirwais, who was born in January 2007, a daughter, Malalai, born in 2012 and another daughter, Howsi, born in March 2014 in Gurgaon, India. He became father once again at the age of 58 when another daughter was born in September 2016 in Apollo Hospital, New Delhi. According to a declaration of his assets by an anti-graft body, Karzai earns $525 monthly and has less than $20,000 in bank accounts. Karzai does not own any land or property.  Karzai has six brothers, including Mahmood Karzai and Qayum Karzai, as well as Ahmed Wali Karzai, deceased, who was the representative for the southern Afghanistan region. Qayum is also the founder of the Afghans for a Civil Society. Karzai has one sister, Fauzia Karzai. The family owns and operates several successful Afghan restaurants in the East Coast of the United States and in Chicago.  In initial biographical news reporting, there was confusion regarding his clan lineage; it was written that his paternal lineage derived from the Sadozai clan. This confusion might have arisen from sources stating he was chosen as the tribal chief, or Khan, of the Popalzai. Traditionally, the Popalzai tribe has been led by members of the Sadozais. The first King of Afghanistan, Ahmad Shah Durrani, was the leader of the Sadozais, and the Sadozai lineage continued to rule Afghanistan until 1826 when the Barakzais ascended to the throne.  Karzai is believed to be from the Shamizai subtribe of the Popalzais. His grandfather, Khair Muhammad Karzai, was a head of the Popalzai tribe from Kandahar who relocated to Kabul and ran the business of a guest house. This allowed Karzai's father Abdul Ahad, to gain a foothold in the royal family, and subsequently, the parliament. These actions and upwards movement within the Popalzai tribal system, led to the Karzai family furnishing a viable Shamizai clan alternative to Sadozai leadership in the aftermath of the Soviet invasion when the Sadozai clan failed to provide a tribal leader. He is often seen wearing a Karakul hat, something that has been worn by many Afghan kings in the past.

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Karzai is believed to be from the Shamizai subtribe of the Popalzais.