Kennedy was born as Myles Richard Bass on November 27, 1969 in Boston, Massachusetts, and subsequently lived in Northern Idaho. As a child, he moved to Spokane, Washington, where he grew up in a Christian Science family on a farm. His father, Richard Bass, died when he was four years old and his mother subsequently went on to marry a Methodist minister, and the family took the surname Kennedy. Before Kennedy attended Mead High School (which he attended with football player Jason Hanson), he found musical inspiration from Led Zeppelin, Marvin Gaye, Stevie Wonder, and John Sykes' Blue Murder band.

In 1995, Kennedy started teaching guitar in a store called Rock City Music. By August 1996, he became the lead vocalist and lead guitarist of The Mayfield Four, a rock band he formed with his childhood friends Zia Uddin, Marty Meisner, and Craig Johnson (also of Citizen Swing). They signed a contract with Epic Records thanks to a critically acclaimed demo called Thirty Two Point Five Hours that the band recorded in 1996, followed by a live extended play called Motion in 1997. The Mayfield Four's debut album, Fallout, was supported with a fifteen-month tour with bands such as Creed, Big Wreck, and Stabbing Westward. The album was praised by critics, but it failed to chart, and ultimately became the only album by the band to feature rhythm guitarist Craig Johnson, who was fired from the band due to undisclosed reasons.  Following the Fallout tour, Kennedy made an appearance in the 2001 drama film Rock Star starring Mark Wahlberg and Jennifer Aniston. He said that he got a call from his manager telling him that the filmmakers needed someone who could sing high and that his name was suggested. On the set of the film, he met Wahlberg along with Zakk Wylde and Jason Bonham, who also appeared in the movie alongside several other notable musicians. Kennedy was the only actor in the movie whose actual singing voice was used. In the movie, directly paralleling a scene at the beginning of the film, Kennedy's character (Mike, also known as "Thor") is noticed by Wahlberg's character, Chris "Izzy" Cole, the lead singer of Thor's favorite band, Steel Dragon. Izzy pulls Thor onstage and sings the rest of the song with him, eventually telling him to finish the rest of the band's concert. The film was met with mostly mixed reviews, garnering a 52% "Rotten" score on Rotten Tomatoes.  The Mayfield Four's second and final album, Second Skin, was released in June 2001. Kennedy has since said that it is one of the most personal records he has made. The album has been critically acclaimed and Kennedy has commented on how it and Fallout are much more popular now than when they were released.  Though popular, The Mayfield Four never garnered enough exposure to break into the mainstream. In 2002, the future of the band began to look unlikely, and Kennedy began recording new music, which he described as "Daniel Lanois meets Massive Attack." The band went on hiatus that year, and would ultimately disband. In an interview with Pulse Weekly in 2004, Kennedy said that it was because he was "burned out with the whole rock industry at that point." However, three previously unreleased songs appeared on a fan-run Myspace page dedicated to and approved by The Mayfield Four in early 2010, causing rumors of a possible reunion to begin circulating. However, when asked about this during an interview, Kennedy replied that he does not see it happening.  Kennedy is best known as the lead vocalist and guitarist of the American hard rock band Alter Bridge. The band's origins lie in late 2003 when Kennedy was contacted by former Creed guitarist Mark Tremonti, who was interested in having Kennedy lay down vocal tracks for some songs he had recently written. Tremonti and drummer Scott Phillips had reunited with former bassist Brian Marshall who had left Creed in 2000 to form a new band. Alter Bridge, taking its name from an actual bridge that used to be located near Tremonti's home in Detroit, was officially formed in January 2004. Coinciding with the official announcement of Alter Bridge's formation was an announcement regarding their debut album, One Day Remains, along with the release of that album's lead single, "Open Your Eyes." One Day Remains was released in 2004 on Wind-up Records. It received generally mixed to negative reviews and was certified Gold by the RIAA. Two other singles, "Find the Real" and "Broken Wings" were released. One Day Remains was the only album by a band with Kennedy as an official member that does not feature his guitar playing, before his 2014 album "World On Fire" as a part of Slash featuring Myles Kennedy and the Conspirators.  Following a successful tour in support of the album, Alter Bridge announced plans for a second release. The album, Blackbird, was released in 2007 on Universal Republic to mostly positive reviews. Unlike One Day Remains, which was largely written by Tremonti, Blackbird featured Kennedy's guitar playing as well as more of his songwriting contributions. Alter Bridge toured in support of Blackbird throughout 2007 and 2008, recording a concert film titled Live from Amsterdam and releasing it in 2009 via Amazon.com. It would later be released in stores in early 2011 after several delays.  Alter Bridge took a temporary break in early 2009 with its members working on other projects, but the band continued writing music throughout the year. The band regrouped later that year to begin work on their third album, AB III, which was released in 2010 on Roadrunner Records worldwide, except for North America where the album was self-released on Alter Bridge Recordings via EMI. For the album, Kennedy chose to write lyrics based on his own personal experiences with faith and believing. As such, it is lyrically the band's darkest album, with Kennedy calling it the most personal album he had made since The Mayfield Four's Second Skin. AB III has received critical acclaim. A second concert film, Live at Wembley, was released on March 26, 2012. The band reunited in late 2012 and recorded from April to July 2013 their fourth album titled Fortress, which was released on September 30, 2013. The band reconvened in January 2016 and, through that July, recorded their fifth album The Last Hero, which was released on October 7, 2016.  Having joined Alter Bridge primarily as lead vocalist, Kennedy began to play rhythm guitar during live performances following the release of One Day Remains. He has since played rhythm guitar on the band's subsequent studio releases, and also played lead tracks on a number of songs and during live performances.  In early 2009, Kennedy announced a solo side project. He described the material as "dreamy" and "[not] aggressive", saving those songs for Alter Bridge. He also said, "It's more singer/songwriter based. I will say it's going to be interesting." He later posted on his Myspace page that he is working with some "great people" and that he has details coming at a future date. Slash announced via Facebook on February 1, 2010 that he would be appearing on Kennedy's solo record, and Kennedy confirmed this via Myspace. Kennedy had originally hoped that his album would be released in early 2010, digitally first and then on CD, but he has since put its release on hold. However, he recently said that he is still too busy to release the album as he stated that he would like to tour to promote it, but he wanted to release it on December 21, 2012, as a joke, although a firm release date has not yet been announced.  When asked if the record would be a departure from his previous work, he replied that it is different and again referred to the singer-songwriter approach that would be featured on it and that it would not be a hard rock album. He also said that "it was maybe the most difficult thing I've ever done in the sense that I didn't have a band." He also said that the music is very intimate and that it features piano as well. In an interview with Guitarist UK magazine, he said that some of the songs will feature jazz, blues, and R&B influences, while others still "get quite atmospheric and ethereal," comparing the sound to Daniel Lanois and Massive Attack, while assuring fans that the rock style will still be present. In the same Guitarist interview, he confirmed the titles of three songs that will appear on his record: "The Light of Day", "Complicated Man", and "The Bar Fly". Most recently, he confirmed that another song will be titled "Love Rain Down". He said in an interview with CraveOnline that "Love Rain Down" differs from anything else he has ever written. In 2017, he said he shelved the songs he had written and started over.  Kennedy has performed two solo benefit concerts: one hosted by Paul Reed Smith and PRS Guitars to benefit cancer patients, and another to benefit abused children. The latter was called Bofest 2009 and was headlined by Kennedy on October 17, 2009.  He has also been at work on his solo project off and on since 2009. His debut solo album, Year of the Tiger, was released on March 9, 2018.

Did he ever release any singles?
He has also been at work on his solo project off and on since 2009.