IN: Tu Youyou (Chinese: Tu You You ; pinyin: Tu Youyou; born 30 December 1930) is a Chinese pharmaceutical chemist and educator. She is best known for discovering artemisinin (also known as qinghaosu) and dihydroartemisinin, used to treat malaria, which has saved millions of lives.

Tu Youyou carried on her work in the 1960s and 70s during China's Cultural Revolution, when scientists were denigrated as one of the nine black categories in society according to Maoist theory (or possibly that of the Gang of Four).  In 1967, during the Vietnam War, Ho Chi Minh, the leader of North Vietnam, which was at war against South Vietnam and the United States, asked Chinese Premier Zhou Enlai for help in developing a malaria treatment for his soldiers trooping down the Ho Chi Minh trail, where a majority came down with a form of malaria which is resistant to chloroquine. Because malaria was also a major cause of death in China's southern provinces including Hainan, Yunnan, Guangxi, and Guangdong, Zhou Enlai convinced Mao Zedong to set up a secret drug discovery project, named Project 523 after its starting date, 23 May 1967. Upon joining the project unit, Tu was initially sent to Hainan where she studied patients who had been infected with the disease. During the time she spent there, her husband was banished to the countryside, meaning that her daughter had to be entrusted to a nursery in Beijing.  Scientists worldwide had screened over 240,000 compounds without success. In 1969, Tu Youyou, then 39 years old, had an idea of screening Chinese herbs. She first investigated the Chinese medical classics in history, visiting practitioners of traditional Chinese medicine all over the country on her own. She gathered her findings in a notebook called A Collection of Single Practical Prescriptions for Anti-Malaria. Her notebook summarized 640 prescriptions. Her team also screened over 2,000 traditional Chinese recipes and made 380 herbal extracts, which were tested on mice.  One compound was effective, sweet wormwood (Artemisia annua), which was used for "intermittent fevers," a hallmark of malaria. As Tu also presented at the project seminar, its preparation was described in a 1,600-year-old text, in a recipe titled, "Emergency Prescriptions Kept Up One's Sleeve". At first, it didn't work, because they extracted it with traditional boiling water. Tu Youyou discovered that a low-temperature extraction process could be used to isolate an effective antimalarial substance from the plant; Tu says she was influenced by a traditional Chinese herbal medicine source, The Handbook of Prescriptions for Emergency Treatments, written in 340 by Ge Hong, which states that this herb should be steeped in cold water. This book contained the useful reference to the herb: "A handful of qinghao immersed with two litres of water, wring out the juice and drink it all." After rereading the recipe, Tu realised the hot water had already damaged the active ingredient in the plant; therefore she proposed a method using low-temperature ether to extract the effective compound instead. The animal tests showed it was completely effective in mice and monkeys.  Furthermore, Tu volunteered to be the first human subject. "As head of this research group, I had the responsibility" she said. It was safe, so she conducted successful clinical trials with human patients. Her work was published anonymously in 1977. In 1981, she presented the findings relating to artemisinin at a meeting with the World Health Organization.
QUESTION: DId she test on people?
IN: A-Teens (stylized as A*Teens) were a Swedish pop music group from Stockholm, Sweden, formed by Niklas Berg in 1998 as an ABBA tribute band called ABBA Teens and later renamed A-Teens. The band members were Marie Serneholt, Amit Sebastian Paul, Dhani Lennevald and Sara Lumholdt. The band's debut album became a success around the world and in 2001 it was reported that the band had sold 6 million albums worldwide. After six years together, the band announced they would take a break in 2004 after the release of their Greatest Hits album.

The band's second album, entitled "Teen Spirit", featured a compilation of tracks that were not ABBA covers and when it was finally released on 26 February 2001, it debuted at number two in the Swedish Charts. This pop sensation hit reached the top ten in other countries and entered at number eighty-three on the World Charts, number thirteen on the European Albums Chart, number fourteen on CNN's WorldBeat Album Charts and peaked at number fifty in the United States selling over 60,000 copies in its first two weeks, ensuring Gold Status for sales exceeding the 500,000 copies in the United States alone. Prior to the release of the album, the A-Teens became one of the first bands to broadcast one of their shows on MSN's Websites.  The UK releases were delayed due to A-Teens' failure with their previous album in that country. When "Upside Down" was released there in May 2001, it became their biggest hit in the country. The single peaked at number ten in the United Kingdom becoming their only top ten hit in that country. The album was delayed and released after the second single, "Halfway Around The World" in late October 2001. The single barely made the top thirty and the album did not chart in the top 75.  Before they started their concert tour in the U.S. the band went to promote their album to Asia, with stops in Japan, Singapore, Malaysia where they did show for MTV Asia and Thailand, with great success, especially in the former where Coca-Cola signed the band to become the face of the brand there and promote, "We were the first international artists ever to appear on a soda can there. They printed 15 million of them; we went home with ten!" Remembers Sara, The cans were distributed around the country that year. Also in 2001, the A-Teens performed as top billing during the Radio Disney Live! 2001 World Tour in Chicago and Philadelphia markets.  The group promoted their album with a forty-three-date tour with Aaron Carter around the U.S. Back in Europe, the band toured with No Angels in Germany. By the end of 2001, Teen Spirit went on to sell over 1 million copies worldwide and were invited by Walt Disney/Buena Vista to record the European soundtrack for the movie "The Princess Diaries". As the movie had already been released in North and South America, the movie was set to be released in Europe in the winter 2001. "Heartbreak Lullaby" a song written by Cathy Dennis (famous for writing Kylie Minogue's number one hit, "Can't Get You Out of My Head") and Kasmanaut, the video was shot in Germany in late October, in the middle of their tour. The single was released in December 2001 and it became another top ten hit for the band in their home country spending four months inside the charts.
QUESTION:
Did anything interesting happen while they toured?