In May 1999, Lee Ryan and Antony Costa met at the ages of 15 and 17, respectively, when auditioning for a boy band on ITV's This Morning, with Simon Cowell putting the group together. Ryan made it into the band, as did 21-year-old Will Young (who would go on to win the first series of Pop Idol in 2002), although Costa was not chosen.  The boy band never took off, but Ryan and Costa remained friends following their meeting. In 2000, Costa and another one of his friends, Duncan James, decided to form their own band, and they were soon joined by Ryan. Their manager Daniel Glatman said, "Duncan came to see me with his friend, Antony Costa, who was also in the same position [wanted to be in the music industry], and they told me that they wanted to do something together. When I asked them if they had anyone in mind to work with, they said they had a friend, Lee Ryan, whom they wanted to invite to join their band. The three of them came in a couple of days later and I was completely blown away by the incredibly talented stars that stood before me." Ryan, Costa, James and Glatman all felt that something was missing and so they went on to audition for a fourth member, a position eventually filled by Ryan's flatmate, Simon Webbe.  Blue started recording for their debut album following their new line-up. They released their debut single "All Rise" in May 2001 and it reached number four on the UK Singles Chart. Their follow-up single "Too Close" was released in August 2001 and peaked at number one. Following this, the band went to New York City to film the "Too Close" music video, and while there, they witnessed the attacks on the World Trade Center. The following month, Blue were being interviewed by British newspaper The Sun and Ryan commented that "This New York thing is being blown out of proportion" and asked "What about whales? They are ignoring animals that are more important. Animals need saving and that's more important." The other members of the band tried to silence Ryan, but he went on. This caused a huge media backlash that resulted in Blue losing a record deal in the United States and campaigns to sack Ryan from the group. Despite the backlash, Blue went on to achieve a second number one in November with the ballad "If You Come Back". The album All Rise was released in time for Christmas and reached number one, eventually selling in excess of 1.8 million copies in the UK. The final single from the album, "Fly by II", reached number six in March 2002.

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